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Indica Vs Sativa Vs Hybrid: The Differences You Need to Know

indica sativa hybrid cannabis types

Indica Vs Sativa Vs Hybrid: The Differences You Need to Know

Cannabis is a versatile plant, and there are different types of cannabis that each have their own unique properties. It’s important to know the characteristics among different cannabis strains so you can select the one that best meets your needs.

By understanding the characteristics, psychoactive effects, benefits, and risks associated with the different strains of cannabis plant, you will be able to make an informed decision when selecting what type of cannabis you should use.

Sativa Vs Indica Vs Hybrid Chart
Sativa Vs Indica Vs Hybrid Chart

Definition of Cannabis 

The cannabis plant is a naturally-occurring plant that has been used for thousands of years. The three main varieties of cannabis are indica, sativa, and hybrid cannabis strains. Each particular strain has its own unique effects and benefits, which can vary widely from one strain to another. In this article, we will compare the differences between indica vs sativa vs hybrid cannabis in detail.

Overview of Different Types of Cannabis – Sativa, Indica, and Hybrid Cannabis 

Different types of cannabis
Different types of cannabis

Sativa plants are very tall and spindly, with long thin leaves. Sativa strains are known to be uplifting and stimulating, making sativa a good choice for daytime activities. Indica cannabis is shorter and wider in stature with wide leaves. Indica strains are known to have more of a sedative effect than sativa varieties.

Indica strains are great for relaxation and are popular with cannabis users for pain, insomnia, stress, depression and anxiety. The effects of indica-dominant strains tend to be more deeply felt throughout the body, allowing users to reach a deeper level of relaxation than sativa varieties.

Hybrid strains are a cross between sativa and indica varieties and are generally considered to be in between sativa and indica in terms of effects. Hybrids are usually bred for specific traits, such as improved flavor or higher yields, but they can also be bred for desired psychoactive effects.

Sativa Cannabis 

Sativa strains
Sativa strains

Sativa strains have been used for centuries due to their energizing effects and flavor profiles. Today they remain some of the most popular cannabis varieties because of their ability to provide an uplifting, stimulating buzz.

Sativa strains of cannabis tend to be more energizing than indica strains. Some people use it during the day to support their energy levels and enhance concentration.

Sativa strains may offer support for mood and stress reduction, and is thought to enhance creativity and mental clarity. Some sativa strains are also thought to have anti-inflammatory effects which may be of interest for those who contend with chronic pain. Some people use this cannabis strain to help alleviate nausea and vomiting.

A number of sativa strains are known for their high THC concentration. Jack Herer, Sour Diesel, and Green Crack are a few sativa strains that contain some of the highest amounts of THC. Other potent cannabis sativa strains include Super Silver Haze, Dancehall, and Dutch Treat.

When looking for a strain that has higher levels of THC, it is important to do research and find out what amount the particular strain contains. Also remember that cannabis affects everyone differently, so what works for one person may not work for another.

Knowing the right sativa strain can make all the difference when trying to get the desired effects from cannabis consumption. With some research and knowledge about cannabis sativas, you can find the perfect strain for you.

Popular Sativa Strains

Popular sativa strains
Popular sativa strains

Sativa strains are popular and widely-used strains of cannabis. They are renowned for their uplifting, energizing, and often cerebral effects. Some of the more popular sativa strains include Durban Poison, Super Silver Haze, and Super Lemon Haze. These sativa strains have been bred to create an energizing high that can be felt both mentally and physically.

Durban Poison

Durban Poison is an incredibly popular sativa strain famous for its sweet smell and flavor reminiscent of anise. It was initially bred in South Africa and is believed to have originated from ancient sativa landrace strains.

Super Silver Haze

Super Silver Haze cannabis is a sativa-dominant strain that is renowned for its high levels of THC and energizing effect. Super Silver Haze cannabis users often report feeling uplifted and energized after consumption. The effects are described as being clear and focused to help improve productivity throughout the day.

This cannabis strain has also been reported to have strong physical effects with deep relaxation in some cases. Some cannabis users use Super Silver Haze cannabis for pain, nausea, insomnia and stress.

Super Lemon Haze

Super Lemon Haze is a cannabis sativa strain that originated in the Netherlands. It’s a popular choice among cannabis users due to its high THC content and refreshing citrus flavor. The aroma of Super Lemon Haze has sweet lemon, pine, and herbal notes that come together to create an enjoyable experience. Consumers report feeling uplifted after consuming this strain, with increased creativity and focus as well as mild euphoria.

Delta 10 Pineapple Express Sativa Tincture by Innovative Extracts

Delta 10 Pineapple Express Tincture
Delta 10 Pineapple Express Tincture

The Delta 10 Pineapple Express Sativa Tincture by Innovative Extracts is an exciting way to take your cannabis experience up a level. This tincture is formulated to provide maximum potency and flavor, with a strong Pineapple Express aroma that will tantalize your senses.

This high quality tincture is made with pure Delta 10 THC oil that has been carefully extracted from high-grade flower using innovative extraction methods developed by the experts at Innovative Extracts.

Unlike other tinctures on the market, this one contains only natural ingredients and no artificial flavors or preservatives—giving you naturally sourced Pineapple Express cannabis terpenes combined with ultra-pure Delta 10 THC oil for maximum cannabinoid potency and flavor. And because it comes in a convenient dropper bottle, it’s easy to get the exact dose you’re looking for. Delta 10 Pineapple Express Sativa Tincture by Innovative Extracts is the perfect way to elevate your cannabis experience.

Indica Cannabis

Indica cannabis
Indica cannabis

Indica is a species of cannabis that originated in the Indian subcontinent. Cannabis indica plants are better adapted to cooler climates and higher altitudes than its sativa counterparts, making it well-suited for outdoor cultivation in areas with milder climates. Unlike sativa, indica has thicker foliage and shorter flowering cycles, and it tends to be hardier against pests and disease.

Indicas are known for their sedative properties. One of the main features of indica effects is that it is felt throughout the body rather than just being experienced in the head. People have chosen indica strains for insomnia, pain relief, stress and anxiety relief, and depression. Indica strains of cannabis may be of interest for some people in managing symptoms associated with conditions such as multiple sclerosis, arthritis and fibromyalgia.

Indica cannabis strains are well known for producing high amounts of THC (tetrahydrocannabinol), the most abundant cannabinoid in cannabis plants. These cannabis strains typically produce short and dense buds, as well as a “body-like” buzz. Their naturally higher concentration of THC can reach more than 20 percent in some cases, making them the preferred choice for recreational marijuana users looking for an intense psychoactive experience.

Despite having high levels of THC, indicas tend to be less overwhelming than sativa cannabis strains thanks to the lower concentrations of other compounds like CBD (cannabidiol). This makes indica cannabis an excellent choice for those seeking cannabis-based relief without the intense euphoria of sativa cannabis strains.

A few well known indica cannabis strains include Hindu Kush, Granddaddy Purple, and Northern Lights.

Popular Indica Strains

Popular Indica strains
Popular Indica strains

These strains are known for their sedative effects, making them a popular choice for those looking to relax and unwind. There are many indica strains available, but a few of the most popular indica strains include Hindu Kush, Northern Lights, and Granddaddy Purple.

Hindu Kush

This is an indica landrace strain that originates from the Hindu Kush mountain region near Afghanistan. This pure indica is renowned by cannabis connoisseurs for its earthy flavor with hints of spice. Its effects can range from relaxation to euphoria and even mild hallucinations.

Granddaddy Purple

Granddaddy Purple is an indica-dominant cannabis strain that has gained a reputation for its intense effects and fruity flavor. Its cannabis flower buds are large and dense, with an aroma of grape, berry, and skunk. Its effects can range from relaxation to increased appetite and sleepiness.

Northern Lights

Northern Lights is another classic indica cannabis strain, originating in Holland before becoming famous worldwide thanks to its powerful narcotic-like psychoactive effects. Its buds are dense and covered in resin, giving it a frosty appearance and an aroma of pungent citrus and sweet earth.

Innovative Extracts’ Northern Lights D8 Oil w/Indica Terpenes

Northern Lights D8 Oil w/Indica Terpenes
Northern Lights D8 Oil w/Indica Terpenes

Innovative Extracts’ Northern Lights tincture is a classic blend of true Indica terpene profiles, providing users with a relaxing experience that’s sure to leave them feeling calm and tranquil. This tincture uses THC suspended in MCT oil, giving it an optimal absorption rate that allows the effects to take hold quickly.

The innovative extraction process used by Innovative Extracts gives this tincture its signature flavor and aroma of earthy pine, citrus and spice evident throughout. Not only does this provide an enjoyable taste but also unlocks the beneficial properties of the cannabinoids present within the blend.

In addition to being lab tested for potency and purity, Northern Lights tincture contains no artificial additives or diluents, giving you a safe and reliable product. Try Northern Lights tincture by Innovative Extracts and experience the calming effects of this tincture with every dose.

Hybrid Cannabis Strains

Hybrid cannabis plants are created when both indica and sativa cannabis strains are cross-bred together. Hybrids can offer a range of effects depending on the ratios of indica vs sativa genetics present in the strain. The most common hybrids will generally give users an energizing high that is accompanied by some physical relaxation.

Some popular hybrid strains are thought to have greater pain-relieving properties than sativa or indica varieties alone. Hybrid cannabis strains are becoming increasingly popular due to their ability to combine the best traits of both sativa and indica plants into one strain.

Sativa dominant hybrids

Sativa dominant hybrid strains, as their name suggests, have a sativa component that is dominant when compared to indica. Sativas are known for providing an uplifting and energizing high that may be helpful in providing mental stimulation and aiding creativity. These strains may also provide physical effects such as gentle muscle relaxation.

Indica dominant hybrids

Indica dominant hybrid cannabis strains typically contain more indica than sativa components. The resulting effects of these hybrids tend to have more of a mellow body high combined with the cerebral effects associated with sativa strains.

They support feelings of relief from stress and anxiety while allowing the user to remain functional throughout the day. Indica dominant hybrid cannabis strains may also possess sedative effects which make them particularly useful for those looking to get a good night’s sleep.

How to choose the best hybrid cannabis strain for you

Sativa-dominant and indica-dominant hybrid cannabis strains provide different sets of effects that may be desirable for different individuals depending on their needs. By combining different cannabis genetics, hybrid strains offer users powerful and distinct effects that can help enhance their overall experience when consuming cannabis products.

It is important to do research and talk with your healthcare provider before making any decisions about what type of cannabis strain might work best for you. Whichever route you take, sativa-dominant or indica-dominant hybrid cannabis strains can offer unique effects.

Most Popular Hybrid Strains

Hybrid strains
Hybrid strains

Sour Diesel

Sour Diesel is a sativa dominant hybrid that offers a powerful cerebral high and leaves users feeling euphoric and energetic. It also has an earthy flavor that some describe as similar to diesel fuel with tones of lemon and citrus. Its aromatic compounds have a pungent, sour, fuel-like scent, making Sour Diesel one of the most recognizable sativa strains on the market today.

Jack Herer

Jack Herer is also sativa dominant, and is named after the cannabis activist Jack Herer who was a major advocate for medical marijuana in the US during his lifetime.

This strain offers an uplifting sativa-dominant hybrid high that is perfect for relieving stress and fatigue while also promoting creativity. Its aroma contains earthy notes with tones of pine and citrus, making it an ideal choice for daytime use.

Super Lemon Haze

Super Lemon Haze is a popular sativa dominant hybrid. Its genetics come from two iconic cannabis strains – Lemon Skunk and Super Silver Haze. The psychoactive effects of this hybrid strain are known to be uplifting and cerebral, making it popular amongst cannabis connoisseurs and recreational users alike.

Green Crack

Another hybrid example is Green Crack. It gets its name from its intensely green buds and fruity aroma which many people compare to mango or peach.

This hybrid combines sativa genetics from its parent strain Skunk with Afghani indica genetics, resulting in an invigorating, cerebral high that starts off with an intense rush of energy before gradually calming down. It has a sweet, fruity flavor with undertones of mango and pineapple.

OG Kush

OG Kush is a hybrid cannabis strain that has become one of the most popular strains among cannabis enthusiasts. It is believed to have originated in Florida and is a cross between Chemdawg, Lemon Thai, and Pakistani Kush genetics. The buds are dense, sticky, and very pungent with an earthy aroma that is often described as being “diesel-like.”

Its effects range from calming relaxation to invigorating euphoria depending on your tolerance level. It is known for its high potency and powerful head buzz that can be quite overwhelming to some users.

OG Kush may offer support for conditions such as stress, depression, migraines, pain relief and nausea. Many experienced cannabis connoisseurs consider OG Kush to be one of the best strains available. It’s a great choice for the cannabis user who is looking for a powerful, energizing high.

Innovative Extracts’ OG Kush D8 & THC-0 Disposable Vape

Og Kush disposable vape
Og Kush disposable vape

Innovative Extracts’ OG Kush D8 & THC-0 Disposable Vape is a 1 gram vape containing a hybrid of two classic strains. The device comes preloaded with D8 and 0% THC distillate, providing an innovative way to experience the powerful effects of OG Kush.

This convenient vape product offers users a higher level of potency than other vaporizers on the market, giving an intense vaping experience without the harshness associated with other devices. The unique combination of compounds found in this vape creates an incredibly smooth and flavorful taste while delivering potent effects that many are sure to enjoy.

With its innovative design and top-notch quality ingredients, you can count on Innovative Extracts’ OG Kush Disposable Vape to provide an enjoyable experience. If you’re looking for a powerful vape with intense flavor, this is the perfect device for you. OG Kush D8 & THC-0 Disposable Vape by Innovative Extracts is sure to provide an enjoyable and innovative experience.

Cannabis potential side effects

Sativa cannabis strains can produce an uplifting, energizing effect, but users may find themselves feeling anxious, paranoid or overwhelmed when exposed to high THC levels that are common in sativa cannabis varieties. Additionally, when used irresponsibly and without caution, it may lead to panic attacks and other mental health issues.

Indica cannabis strains can potentially produce undesirable side effects which may include increased heart rate, dry mouth and eyes, redness in the eyes, short-term memory loss, sleepiness or drowsiness during the day, anxiety or paranoia, changes in mood and behavior, impaired coordination and reflexes.

Some people may also experience hallucinations or delusions when using cannabis products.

Use cannabis responsibly by starting with small amounts and gradually increasing your dosage over time to become familiar with the effects of the strain you are using. Cannabis affects everyone differently, so it is important to experiment and find the strain that works best for you.

Sativa, indica and hybrid strains of cannabis all have their own unique characteristics, benefits, and risks. Understanding the differences between these plants is key to selecting the type of cannabis that best meets your needs.

Consult with your medical practitioner first

It is always advisable to consult with a healthcare professional prior to using any form of cannabis, especially for individuals with pre-existing mental health conditions.

By being mindful of potential risks associated with cannabis use, users can ensure they are using cannabis in a safe and responsible manner.

With knowledge of the different types of cannabis available and advice from your doctor, you can make an informed decision about which type will offer the most therapeutic support for your individual condition.

Know your local laws on cannabis consumption

Many areas still consider cannabis illegal, so always be aware of your local laws before using any form of cannabis.

Always purchase from a reputable source in order to ensure quality and safety.

Innovative Extracts
Innovative Extracts

References

Kuhathasan, N., Minuzzi, L., MacKillop, J. et al. An investigation of cannabis use for insomnia in depression and anxiety in a naturalistic sample. BMC Psychiatry 22, 303 (2022). https://doi.org/10.1186/s12888-022-03948-6

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CBDA vs CBD: Comparing the Two Cannabinoids And Their Benefits

CBDA vs CBD

CBDA vs CBD: Comparing the Two Cannabinoids And Their Benefits

Introduction

You may have heard of CBD, or cannabidiol, non-psychoactive component found in cannabis and hemp plants. Unlike THC, the compound in cannabis that produces a “high” when ingested, it won’t give you a buzz. CBD is used for its calming and anti-inflammatory benefits.

But there is more to Cannabis and hemp than just CBD and THC; other powerful compounds exist within raw cannabis and hemp plants, such as CBDA (cannabidiolic acid), the acid precursor to CBD. This lesser-known cannabinoid also offers a range of potential therapeutic effects.

In this blog post on CBDA vs CBD, we’ll provide an overview of the two cannabinoids and explore the similarities and differences between them along with their potential applications for improving human health.

What are cannabinoids?

Hemp plants
Hemp plants

Cannabinoids are a complex and fascinating group of chemical compounds found in hemp and cannabis plants, with over 100 different types identified to date. These compounds interact with the body’s endocannabinoid system, a complex network of cell receptors and neurotransmitters that helps regulate various physiological functions such as mood, appetite, pain, and sleep.

The most well-known cannabinoid is tetrahydrocannabinol (THC), a psychoactive compound which is responsible for the “high” commonly associated with cannabis use. CBD is another well-known cannabinoid and has been shown to have multiple therapeutic benefits.

Hemp and cannabis are both strains of Cannabis Sativa with different chemical compositions. Cannabis plants are cultivated for recreational and medicinal purposes, while certain strains of hemp are grown specifically for their high levels of CBD and low levels of THC to produce CBD oil and other beneficial cannabinoid-based products.

Cannabinoids have become the focus of considerable scientific research and are being studied for their potential applications in a range of medical conditions, from chronic pain to anxiety and depression. 

What is CBD?

CBD formula
Chemical structure of CBD

Cannabidiol (CBD) is a cannabinoid derived from the cannabis plant. Its molecular structure interacts with the body’s endocannabinoid system, a network of receptors and molecules that help regulate a variety of physiological processes.

Scientists have been especially interested in studying CBD because of its potential medicinal properties. Research has unveiled a wide range of potential health benefits ranging from anti-inflammatory, anti-prolific, analgesic, anxiolytic, and neuroprotective benefits.

CBD does not have psychotropic properties and will not produce the “high” commonly associated with cannabis. CBD oil and other CBD products such as edibles are widely available.

The hemp plant does not directly produce CBD. Instead, it produces CBDA which is then converted to CBD through a process called thermal decarboxylation.

Decarboxylation

When cannabis is smoked, CBDA converts to CBD.
When cannabis is heated, CBDA converts to CBD.

During decarboxylation, a series of chemical reactions occurs that releases a carbon dioxide molecule and removes the carboxyl group- the acidic part- from CBDA, which converts it into CBD.

The combination of heat and time causes the transformation from CBDA to CBD. The process is fairly simple when cannabis is smoked or heated for cooking. However, to make products such as CBD oil and edibles, a more involved and precise process is involved. CBDA is subjected to time-specific, controlled temperatures that are hot enough to cause decarboxylation, but not so hot that the cannabinoid loses any of its beneficial properties.

What is CBDA?

Chemical structure of CBDA
Chemical structure of CBDA

Cannabidiolic acid (CBDA) is a natural compound found in the raw form of the hemp and cannabis plant. It is present in high concentrations in the plant’s tissues, and serves as the precursor of CBD due to its acidic form.

CBDA benefits are similar to those of CBD but there are some differences.  

How does CBDA work?

Despite being a lesser-known compound in the cannabis plant, CBDA shows promise in treating various ailments such as arthritis, cancer, anxiety, and nausea.

One of the ways CBDA interacts with the body is through the endocannabinoid system, specifically the CB1 receptor, which is responsible for regulating mood, appetite, and pain.

CBDA also inhibits the cyclooxygenase-2 (COX-2) enzyme, which is responsible for inflammation and pain in the body. By inhibiting this enzyme, CBDA shows potential therapeutic value in managing various inflammatory conditions.

In addition, CBDA is thought to activate the 5-HT1A serotonin receptor, which may also contribute to its anti-inflammatory and anti-nausea effects.

How is CBDA made?

Chemical structure of CBGA
Chemical structure of CBGA

CBDA is formed from its precursor, cannabigerolic acid (CBGA).

What is CBGA?

Sometimes referred to as the “mother of all cannabinoids”, CBGA is the precursor from which all other cannabinoids are derived. It is the most abundant compound found in the cannabis or hemp plant’s trichomes, which are hair-like glandular structures located in the buds and leaves of the cannabis plant.

Once CBGA interacts with plant enzymes in the trichomes, it forms into three major cannabinoid precursor compounds: Tetrahydrocannabinolic acid (THCA), Cannabichromenic acid (CBCA), and Cannabidiolic acid (CBDA).

Then, when the raw hemp or cannabis is exposed to sunlight and/or heat, a process called decarboxylation takes place and CBDA converts into CBD.

Why isn’t CBDA well known?

Upon initial analyses, CBDA was believed to have little therapeutic value, as acidic forms of cannabinoids were presumed to serve only as precursors to cannabinoids like CBG, CBD, and THC. As a result, the scientific community showed little interest in acidic, unstable cannabis compounds.

In 2008, researchers noticed a striking similarity between the molecular structure of CBDA and existing nonsteroidal anti-inflammatory drugs (NSAIDs). Upon further study, they found that CBDA demonstrated the same COX-2 inhibitory characteristics that make NSAIDs beneficial in managing inflammation, warranting further study of CBDA.

A Difficult research subject

Another reason CBDA’s properties were not known until recently is because CBDA is a problematic substance for scientific study. It is an unstable compound, which makes it difficult to isolate and manipulate.

CBDA rapidly decarboxylates — losing its carboxyl group and becoming CBD — when the plant material is exposed to heat, light, oxygen, or other environmental factors.

Furthermore, CBDA has a very short half-life in the body, meaning that it is quickly broken down and eliminated. All of these factors have presented significant obstacles in studying CBDA.

Stabilized form of CBDA

R. Mechoulam, the cannabis scientist who first synthesized THC and CBD, recently devised a method to overcome the instability of CBDA, allowing for more reliable research into its potential therapeutic benefits.

He and his research team successfully synthesized CBDA into a more stable compound, thus enabling a consistent basis for studying it across various medical applications. This has opened up exciting new avenues for exploring possible CBDA benefits and therapies.

Are CBD and CBDA the same thing?

No, but there is a relationship between the two. Although CBD and CBDA belong to the same family of cannabinoids and offer some similar health benefits, they differ in their chemical structure, properties, and effects on the body.  

CBD vs CBDA

Taking a CBD tincture
Taking a CBD tincture

Similarities between CBDA vs CBD

The main similarity between CBD and CBDA is that they do not have psychotropic properties, which means that consuming them will not cause the user to become high.

CBD and CBDA interact with the endocannabinoid system, a network of receptors and molecules involved in regulating various physiological processes such as pain relief, immune modulation, and mood regulation. CBD and CBDA have been found to have neuroprotective, anti-oxidant, and anti-proliferative properties.

CBDA and CBD inhibit the production of cyclooxygenase-2 (COX-2) enzymes, a key player in the inflammatory response. This makes them potential candidates for treating conditions characterized by inflammation and pain such as arthritis or Crohn’s disease.

So what is the difference between CBDA vs CBD?

The main difference between CBDA and CBD is that one is the precursor of the other, meaning that CBDA converts to CBD through the decarboxylation process.

CBD and CBDA exhibit some distinct differences in how they interact with the human body.

Although both CBDA and CBD have been found to inhibit COX-2 enzymes from producing inflammatory compounds, some studies found that CBDA boosts activity in the endocannabinoid system without binding to cannabinoid receptors at all.

Greater bioavailability

CBDA has a higher degree of bioavailability than CBD, meaning it is more easily absorbed and used by the body.

Its higher bioavailability is due to its unique chemical structure that allows it to easily pass through cell membranes and interact more effectively with the endocannabinoid system. 

How to take CBD and CBDA

Raw hemp smoothie
Raw hemp smoothie

CBD and CBDA products can be found in capsule, tincture, topical creams, and edible forms.

High-quality CBD oils are easy to find, but finding quality CBDA oils can be difficult to source, as acidic cannabinoids are more challenging to extract and stabilize. Those currently available come in several forms: CBDA Isolate, Broad Spectrum, and Full Spectrum.

A key factor in finding quality CBD and CBDA products is understanding where and how the oil was sourced. It is recommended to choose brands that use organic hemp, do not use artificial additives, have a third-party testing system in place, and provide clear indication of the dosages.

Some health conscious cannabis users are consuming CBDA by juicing raw hemp and adding it to smoothies to fully access its therapeutic properties. Unfortunately, CBDA products like raw cannabis juice are not widely available yet.

CBD and CBDA Benefits

CBDA and CBD show therapeutic potential for a range of health conditions.
CBDA and CBD have anti-inflammatory properties.

Inflammation

Inflammation is a complex process that involves many different biological pathways. Among the cannabinoids, CBD and CBDA are some of the most promising for their potential to relieve chronic inflammatory conditions such as arthritis and Crohn’s disease.

A recent study comparing the anti-inflammatory effects of CBD and CBDA found that they each reduce inflammation through unique mechanisms.

CBD and CBDA inhibited the activity of several key pro-inflammatory cytokines, but CBDA went a step further by inhibiting the production of nitric oxide, a potent pro-inflammatory molecule.

Additional studies suggest that the anti-inflammatory effects of CBDA are as effective as nonsteroidal anti-inflammatory drugs.

Neuroprotection

The brain has many CB1 receptors.
Numerous CB1 receptors are located in the brain.

Research indicates that the anti-inflammatory properties of CBD and CBDA seem to reduce neurological damage caused by inflammation, toxins, or injury, and may be useful in preventing or treating various neurological conditions.

The cannabinoids work by interacting with CB1 and CB2 receptors in the brain and regulating neurotransmitter levels to alleviate inflammation, oxidative stress, and excitotoxicity in the brain, all of which are linked to neurodegeneration.

These findings provide a scientific basis for the use of CBD and CBDA as neuroprotective agents, opening up new avenues for the development of treatments for various neurological disorders like Parkinson’s disease, Alzheimer’s disease, and multiple sclerosis.

Cancer

Scientists are studying the antiproliferative and proapoptotic properties of CBDA and CBD.
Scientists are studying the antiproliferative and proapoptotic properties of CBDA and CBD.

In studies, CBD and CBDA have exhibited antiproliferative and proapoptotic activities- meaning they prevented cancer cells’ growth and spread- on several types of cancer cells, including breast, lung, colon, and prostate cancers.

Scientists have also found that CBDA induces apoptosis, or cell death, in cancer cells while leaving healthy cells untouched. These findings suggest that CBDA has potential as a more targeted and less harmful alternative to traditional cancer treatments such as chemotherapy.

Nausea

The anti-emetic effects of CBD and CBDA have drawn interest interest from the scientific world due to their ability to interact with serotonin receptors in the brain, which play a crucial role in regulating nausea and vomiting. In studies, consumption of CBDA or CBD produced little to none of the side effects of traditional anti-emetic medications.

Additionally, CBD and CBDA appears to reduce the activity of certain neurotransmitters in the brain, further contributing to their anti-emetic effects.

A Canadian study found that CBDA was significantly more effective than CBD in binding to serotonin receptors linked to anti-nausea and anti-anxiety effects when given along with low doses of the traditional anti-nausea drug ondansetron for chemotherapy patients. This finding was measured as being one hundred times more powerful.

Epilepsy

The anti-inflammatory and neuroprotective effects of CBD and CBDA make them potentially valuable treatment options for epilepsy, a debilitating neurological disorder affecting millions worldwide. Although both cannabinoids possess strong anticonvulsant properties, they each work differently.

CBDA‘s anticonvulsant properties are attributed to its unique mode of action on the endocannabinoid system. CBDA interacts with the CB1 and CB2 receptors, modulating the GABAergic and glutamatergic neurotransmitter systems, thereby reducing seizure activity. In several studies involving animal models, CBDA reduced the frequency and severity of epileptic seizures.

The underlying mechanisms of how CBD works to reduce seizures are not yet fully understood. Scientists think that it interacts with receptors in the brain that play a role in regulating seizures.

New research by scientists at NYU Grossman School of Medicine suggests that CBD prevents seizures from occurring by reducing hyperexcitability in neurons and inhibiting the synaptic effects of lysophosphatidylinositol, an endogenous membrane phospholipid.

Mood disorders

CBDA and CBD may have anxiolytic properties.
CBDA and CBD are being studied for their potential anxiolytic properties.

Anxiety is a common mental health issue that affects many people around the world. Studies suggest that both CBD and CBDA may help reduce symptoms of generalized anxiety disorder, social anxiety disorder, and post-traumatic stress disorder.

CBD, which is known for its calming effect, interacts with CB1 and CB2 receptors in the brain to affect serotonin levels, thus stabilizing mood and relieving anxiety. On the other hand, CBDA seems to work in a slightly different manner to regulate serotonin by interacting with the 5-HT receptors located throughout the body.

Serotonin, a neurotransmitter involved in regulating moods, is greatly affected by the activity of the 5-HT1A receptor. CBDA has a greater affinity to the 5-HT1A receptor than CBD, suggesting it may have more potent anxiolytic effects.

Depression

CBD and CBDA are being studied for their potential as therapeutic options for depression. It appears that CBDA works similarly to antidepressant drugs but without some of the side effects. Furthermore, CBDA may be effective at doses far lower than those used for CBD— ten to 100 times less.  This could make it a more cost-effective treatment option.

CBDA vs CBD: summary

Overall, CBDA and CBD offer diverse health benefits that may be of use to a wide variety of individuals. The data regarding the potential benefits of CBDA is only beginning to emerge; however, it seems to hold promise in treating many ailments and diseases. Although further research is needed, it appears that these CBD and CBDA have the potential to improve overall wellness.

Some caution should be used when exploring the use of cannabinoids since there may be legal, safety and overall health implications.

CBDA and CBD oils may not be the perfect fit for everyone. While these oils are generally safe and well-tolerated by most individuals, it is important to be aware of potential interactions with other medications. This is why it is important to consult with a medical professional before incorporating CBD or CBDA into a daily supplement routine. A qualified healthcare provider can provide guidance on recommended dosage accounts and assess how CBD or CBDA interacts with other prescription medications currently being taken.

For further reading

Campos AC, Fogaça MV, Sonego AB, Guimarães FS. Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacological Research. 2016 Oct;112:119-127. doi: 10.1016/j.phrs.2016.01.033. Epub 2016 Feb 1. PMID: 26845349.

Formato, Marialuisa et al. “(‒)-Cannabidiolic Acid, a Still Overlooked Bioactive Compound: An Introductory Review and Preliminary Research.” Molecules (Basel, Switzerland) vol. 25,11 2638. 5 Jun. 2020, doi:10.3390/molecules25112638 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321064/#B40-molecules-25-02638

Gusho, Charles A, and Tannor Court. “Cannabidiol: A Brief Review of Its Therapeutic and Pharmacologic Efficacy in the Management of Joint Disease.” Cureus vol. 12,3 e7375. 23 Mar. 2020, doi:10.7759/cureus.7375 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176325/

Hirao-Suzuki M et al. 2020. “Cannabidiolic Acid Dampens the Expression of Cyclooxygenase-2 in MDA-MB-231 Breast Cancer Cells: Possible Implication of the Peroxisome Proliferator-activated Receptor β/δ Abrogation.” Journal of Toxicology Science, 45(4):227-236. doi: 10.2131/jts.45.227. PMID: 32238697. https://pubmed.ncbi.nlm.nih.gov/32238697/

Kim, Juyong et al. 2023. “The Cannabinoids, CBDA and THCA, Rescue Memory Deficits and Reduce Amyloid-Beta and Tau Pathology in an Alzheimer’s Disease-like Mouse Model.” International Journal of Molecular Sciences vol. 24,7 6827. 6, doi:10.3390/ijms24076827 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095267/

Kleinhenz, M. D. et al. 2022. “Short Term Feeding of Industrial Hemp With a High Cannabidiolic Acid (CBDA) Content Increases Lying Behavior and Reduces Biomarkers of Stress and Inflammation in Holstein Steers.” Scientific Reports vol. 12,1 3683, doi:10.1038/s41598-022-07795-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901777/

Maroon J, Bost J. Review of the neurological benefits of phytocannabinoids. Surgical Neurology International 2018 Apr 26;9:91. doi: 10.4103/sni.sni_45_18. PMID: 29770251; PMCID: PMC5938896. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938896/pdf/SNI-9-91.pdf

Rock, E M, & Parker, L. A. “Effect of low doses of cannabidiolic acid and ondansetron on LiCl-induced conditioned gaping (a model of nausea-induced behaviour) in rats.” British Journal of Pharmacology vol. 169,3 (2013): 685-92. doi:10.1111/bph.12162 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682714/

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CBN and THC: How do they differ and what benefits do they offer?

CBN and THC therapeutic uses

CBN and THC: How do they differ and what benefits do they offer?

The cannabis sativa plant is complex, containing dozens of cannabinoids that have unique and varied effects. Two well-known and widely studied cannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabinol (CBN) both found in medical marijuana. While they both offer therapeutic benefits, they differ in their structure, psychoactive effects, and medical applications.

Research indicates that THC and CBN have significant therapeutic potential for a variety of health conditions and may provide neuroprotective properties as well.

Despite some similar uses for each cannabinoid, understanding the differences between THC and CBN is key to discovering their individual potentials as medical treatments.

In this article, we will discuss how CBN and THC interact with the body, their respective health benefits and side effects, and how these cannabinoids can be used to treat various conditions. Read on to find out more about the differences between CBN and THC.

What are CBN and THC?

CBN

Chemical structure of CBN
Chemical structure of CBN

Cannabinol (CBN), is an oxygenated cannabinoid that is formed when THC degrades over time. Although it is considerably less potent than THC, CBN is valued for its potential therapeutic applications in managing insomnia, inflammation, and pain management.

The primary difference between CBN and THC is that CBN does not have any psychoactive properties like the THC found in medical cannabis. This means that it does not create a “high” when it is consumed.

CBN tends to interact primarily with cannabinoid receptors distributed in the peripheral body. These receptors are a component the body’s endocannabinoid system, a complex network of receptors, enzymes, and molecules responsible for regulating crucial physiological processes like mood, appetite, and pain perception. CBN works by binding to CB1 receptors, primarily located in the central nervous system, and CB2 receptors, mainly found in the immune system. These interactions trigger a cascade of reactions that can produce different effects on the body, including sedation, anticonvulsant, and anti-inflammatory properties. 

How CBN is made

The production of CBN is a process that involves the degradation of THC, the primary psychoactive component found in the marijuana plant. This degradation occurs over time and is affected by factors such as temperature and light exposure. Once THC degrades, it transforms into CBN. However, in order to produce CBN on a larger scale, the degradation process is typically accelerated through various methods, such as heating or exposing the plant material to air. After the THC is degraded, the resulting CBN can be isolated and purified for use in various applications, such as in the production of medicinal compounds.

THC

Chemical structure of THC
Chemical structure of THC

Tetrahydrocannabinol (THC) is a lipid-soluble compound with a molecular structure similar to anandamide–a naturally occurring endocannabinoid found in humans. THC is famous for its mind-altering properties, producing an intoxicating sensation commonly associated with the stereotypical “high” from marijuana.

Like CBN, THC acts upon the endocannabinoid system, binding to CB1 and CB2 receptors found throughout the central nervous system and peripheral tissues, respectively. Upon binding to these receptors, THC mimics endogenous cannabinoids, modulating various signaling pathways and eliciting physiological responses. The impact of THC on CB1 receptors in the brain accounts for its psychoactive properties and triggers a series of cellular events that influence various physiological functions, such as pain perception, mood, memory, and appetite.

THC in medicinal products

THC is an active ingredient in several FDA approved medications.

The medical use of THC has been a contentious issue for years. Cannabis as a plant is listed in Schedule I by US federal law under the Controlled Substances Act for having “no accepted medical use”. However, recent developments in research have led to the approval of FDA regulated drugs containing THC. These medications are intended to treat a variety of conditions, such as nausea, chronic pain, and muscle spasms associated with multiple sclerosis.

One such medication is Dronabinol (Marinol), which is used to treat patients suffering from nausea and vomiting caused by chemotherapy, as well as to stimulate appetite in patients with AIDS-related wasting syndrome. Nabiximols (Sativex) is another drug that contains THC and cannabidiol (CBD), and is used to treat spasticity in multiple sclerosis patients. These medications have undergone extensive clinical trials and have been deemed safe and effective by the FDA.

Despite its psychoactive properties, THC has been shown to have medicinal benefits, leading to its inclusion in approved medications. As research into the potential uses of cannabinoids for medical use continues to expand, we can expect to see more FDA regulated products containing THC in the future.

The endocannabinoid system

Part of the endocannabinoid system, cannabinoid receptors are located throughout the body.
Part of the endocannabinoid system, cannabinoid receptors are located throughout the body.

To understand how CBN and THC work, one must first recognize the crucial role of the endocannabinoid system within the body. The endocannabinoid system is a complex network of endogenous cannabinoid receptors and signaling molecules that function to maintain physiological homeostasis in the human body. This system consists of three main components: the endocannabinoids, the cannabinoid receptors, and the enzymes responsible for the synthesis and degradation of these signaling molecules.

Endocannabinoids

Endocannabinoids are lipid signaling molecules that bind to cannabinoid receptors. Once activated, these receptors trigger a variety of physiological responses, including pain modulation, appetite regulation, immune function, and mood regulation. Endocannabinoids are similar in structure to cannabinoids found in cannabis, which is why cannabinoids like CBN and THC interact well with the receptors that make up the endocannabinoid system. 

Cannabinoid receptors

The primary function of cannabinoid receptors is to modulate synaptic transmission and maintain homeostasis in the body.

The two primary types of cannabinoid receptors are CB1 and CB2, which are found in different parts of the body and have distinct functions. CB1 is primarily found in the brain and nervous system, whereas CB2 is found in immune cells and other peripheral tissues.

When activated by endocannabinoids or external cannabinoids, such as those found in cannabis, these receptors send signals to help control these processes and regulate a range of physiological processes. Specifically, cannabinoid receptors mediate the effects of endogenous cannabinoids, such as anandamide and 2-arachidonoylglycerol, as well as cannabinoids derived from the cannabis plant.

Enzymes

Enzymes play a crucial role in the endocannabinoid system by breaking down certain cannabinoids and ensuring that they do not accumulate to harmful levels. Among these enzymes are fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). While FAAH breaks down anandamide, MAGL breaks down 2-AG. Enzymes also help to activate or inhibit the signaling pathways triggered by endocannabinoids.

Therapeutic benefits of CBN and THC

CBN and THC provide promising therapeutic avenues for treating a wide range of inflammatory disorders and neurodegenerative diseases by modulating the immune system’s response to inflammation without inducing side effects that are commonly associated with traditional nonsteroidal anti-inflammatory drugs.

Reduces inflammation

Chronic inflammation is involved in a number of diseases.
Chronic inflammation is involved in a number of diseases.

Inflammation is the body’s response to injury or infection, and under normal circumstances it is the first step in the healing process. However, continuous chronic inflammation deviates from the healing process and is a primary risk factor for development of various diseases such as arthritis, heart disease, multiple sclerosis, and Crohn’s disease.

CBN

CBN has gained considerable attention in the scientific community for its potential to reduce inflammation. The anti-inflammatory properties of CBN can be attributed to its role in moderating the immune response, which normally activates in response to injury or infection but can become unregulated in chronic inflammatory conditions.

At a molecular level, CBN interacts with the endocannabinoid system by binding to cannabinoid receptors, mainly CB2 type receptors located on immune cells. This interaction triggers a cascade of signaling events that ultimately dampens the production of pro-inflammatory molecules and cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), which are commonly elevated in inflammatory conditions.

THC

THC also possesses anti-inflammatory properties. Like CBN, it interacts with the endocannabinoid system as it binds to cannabinoid receptors in various tissues, including immune cells. THC reduces the activity of the immune cells responsible for triggering inflammation, leading to less inflammation and thus less pain and tissue damage. THC may also improve blood flow to inflamed areas, promoting healing. Additionally, THC has been shown to decrease the levels of pro-inflammatory molecules such as interleukin-1 and tumor necrosis factor-alpha.

Neuroprotective properties

Mitochondria are structures that serve as the powerhouse of cells and ensure an adequate supply of energy for neurons to function properly. CBN has been shown to protect these critical cellular components from damage due to chemical and oxidative stress, making it an essential factor in maintaining healthy neuron function. Research on this matter has indicated that CBN activates a number of anti-inflammatory pathways, promoting mitochondrial integrity and facilitating neuroprotection. Thus, CBN appears to be a promising candidate for neuroprotection through its unique capabilities in preserving the life-sustaining qualities of mitochondria within neurons.

Some research findings suggest that THC also has neuroprotective properties due to its ability to activate cannabinoid receptors in the brain. This interaction with receptors leads to a decrease in oxidative stress and inflammation, which in turn reduces damage to neurons and improves overall brain function. While further research is needed to fully understand the extent of THC’s neuroprotective effects, the findings thus far are encouraging and suggest that the THC in medical marijuana may have potential as a therapeutic option for some neurodegenerative diseases.

Reduces anxiety

One of the more significant benefits of CBN is its ability to alleviate anxiety, a pervasive mental health issue that affects millions around the world. The interaction between CBN and the endocannabinoid system can lead to a reduction in anxiety without the unwanted side effects that come with traditional anti-anxiety medication.

CBN binds to the CB1 receptors in the brain where anxiety is a commonly regulated process. This binding process can enhance the inhibitory effects of GABA neurotransmitters, which are involved in decreasing the activity in the brain’s anxiety centers and promoting relaxation.

CBN also increases levels of anandamide, an endocannabinoid that promotes feelings of happiness and wellbeing, further increasing its potential as an anxiety-reducing agent.

Sleep aid

CBN can help with getting a good night's sleep.
CBN can help with getting a good night’s sleep.

CBN is known for its gentle sedative properties, making it a viable treatment option for individuals with sleep disorders like insomnia, as it can increase sleep time and reduce the frequency of waking up during the night.

CBN works to promote sleep by binding to CB1 receptors in the brain which are responsible for controlling sleep-wake cycles. As it binds to these receptors, it increases levels of GABA (a neurotransmitter that promotes relaxation) while decreasing levels of glutamate (a neurotransmitter that promotes alertness). This combination of effects can induce a state of sedation and promote a more restful sleep.

CBN also enhances the effects of other cannabinoids, such as THC, and may help to prolong their sleep-inducing effects. 

Reduces chronic pain

CBN shows great therapeutic potential in pain management through its several interactions with the body. It binds to CB1 and CB2 receptors in the brain, spinal cord, and immune system. Once it binds to these receptors, it prevents the release of inflammatory cytokines, which are responsible for pain in the affected area.

CBN also interacts with vanilloid receptors which are key players in chronic pain signaling, thereby reducing pain sensations. CBN also enhances the production of anandamide, an endocannabinoid that regulates pain and mood.

Studies suggest that THC appears to have pain-relieving properties as well and can ease chronic pain that is often associated with conditions such as multiple sclerosis, arthritis, and cancer.

As THC interacts with the CB1 and CB2 receptors, it indirectly reduces pain transmission by decreasing the amount of neurotransmitters released. This process involves numerous pathways, including the suppression of inflammatory responses, reduction of neuronal excitability, and modulation of descending pain pathways. THC can also cause the release of dopamine and other neurotransmitters, which can positively influence the perception of pain. 

Alleviates nausea

THC has demonstrated significant efficacy as an antiemetic agent for the management of chemotherapy-induced nausea and vomiting.

THC works by activating the cannabinoid receptors in the brain that are responsible for regulating the emetic reflex. These receptors are located in areas of the brain that control nausea and vomiting, including the dorsal vagal complex, area postrema, and nucleus of the solitary tract.

By binding to these receptors, THC suppresses the signaling of neurotransmitters such as serotonin and dopamine, which are implicated in nausea and vomiting.

As a result, THC has become a popular adjunct therapy for cancer patients undergoing chemotherapy and radiation, who often experience debilitating nausea and vomiting as a side effect of treatment.

Stimulates appetite

THC may help increase appetite.
THC may help increase appetite.

THC also stimulates the release of the hormone ghrelin, which has appetite-stimulating effects and may help as an appetite stimulant for people with AIDS and counteract the anorexia associated with chemotherapy or gastrointestinal surgery.

Anticonvulsant

CBN has demonstrated anticonvulsant properties, making it an effective treatment option for individuals with epilepsy. When it interacts with the CB1 receptors located in the brain and its associated neural networks, it modulates the activity of the neurotransmitters that are responsible for controlling seizures. CBN’s potential anti-inflammatory and pain-relieving effects may also contribute to its effectiveness in reducing the frequency and intensity of seizures in individuals with epilepsy, providing much-needed relief for those who suffer from this debilitating condition.

CBN and THC have been studied for their potential in treating a number of conditions, such as anxiety disorders, inflammation-related diseases, neurodegenerative diseases, and depression. Apart from their wide range of beneficial properties, they have many more medical benefits that are yet to be fully explored. Thus, the potential benefits of CBN and THC are far-reaching, and research is ongoing to further explore their effects.

Potential side effects

Allergic reactions to cannabis compounds are rare but not unheard of. There may be an increased risk of certain side effects if CBN or THC is taken in large amounts. Side effects of CBN include dry mouth, dizziness, low blood pressure, sedation, drowsiness, nausea and vomiting. Common side effects of THC include confusion and disorientation as well as changes in appetite or mood.

Interaction with other medications

It should be noted that both compounds may potentially interact with over-the-counter and prescription medications. It is best to consult with a medical professional before consuming either one for medicinal purposes. As with any drug, they should not be used when consuming alcoholic beverages.

Overall, they each offer different medicinal properties that can be beneficial for certain medical conditions. While CBN and THC may have side effects when consumed in large amounts, there is insufficient evidence of severe adverse events occurring from taking either compound. Their medicinal properties are worth exploring further as more clinical research that is conducted.

Summary

CBN and THC can offer many health benefits.
CBN and THC can offer many health benefits.

THC is the primary psychoactive compound in cannabis that produces the ‘high’ sensation. Nonetheless, beyond its psychoactive effects, THC offers significant medical benefits, leading to its inclusion in FDA approved medications. It has been shown to reduce nausea from chemotherapy, increase appetite, lower inflammation, and is an effective pain reliever. THC shows promise in treating symptoms of illnesses like multiple sclerosis, fibromyalgia, and epilepsy.

CBN is known for its gentle sedative properties, making it an effective sleep aid. Scientific and anecdotal evidence suggests CBN possesses anti-inflammatory, anti-anxiety, and neuroprotective properties and may provide therapeutic benefits for medical conditions including inflammation, chronic pain, epilepsy, and anxiety.

Unlike THC, CBN is non-psychoactive, meaning it does not produce a “high” or intoxication. It appears to have a positive safety profile and few if any side effects.

Although there is minimal risk, CBN and THC may cause drug interactions with other substances and medications, so they should be used cautiously and with advice from a healthcare professional before consuming either one for medicinal purposes.

The medical benefits of CBN and THC have been well established in the literature. Additional research is necessary to understand further potential uses in treating various medical conditions. With more research being conducted, we can expect further advances in the understanding and application of these cannabinoids for therapeutic use in the future.

References

For further information on therapeutic uses of cannabinoids, the following literature sources are provided.

Basharat, B., et al. “Hypersensitivity Reactions to Marijuana.” The Journal of Allergy and Clinical Immunology, vol. 127, 2, supplement AB178, (2011). https://doi.org/10.1016/j.jaci.2010.12.707

Hampson, A J et al. “Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants.” Proceedings of the National Academy of Sciences of the United States of America, vol. 95, 14 (1998): 8268-73. https://pubmed.ncbi.nlm.nih.gov/9653176/

Liang, Zhibin et al. “Cannabinol Inhibits Oxytosis/ferroptosis by Directly Targeting Mitochondria Independently of Cannabinoid Receptors.” Free Radical Biology & Medicine, vol. 180 (2022): 33-51. doi:10.1016/j.freeradbiomed.2022.01.001 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840979/

Miller, Henry P., et al. “The Effects of Delta-9-Tetrahydrocannabinol (THC) on Inflammation: A Review.” Cellular Immunology, vol. 352, Apr. 2020, p. 104111 https://doi.org/10.1016/j.cellimm.2020.104111

National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda. “The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research.” Washington (DC): National Academies Press (US); 2017 Jan. 12, 4, Therapeutic Effects of Cannabis and Cannabinoids. Available from: https://www.ncbi.nlm.nih.gov/books/NBK425767/

Yang, L., et al., “Cannabinoid Receptor CB2 Is Involved in Tetrahydrocannabinol-Induced Anti-Inflammation against Lipopolysaccharide in MG-63 Cells”, Mediators of Inflammation, vol. 2015, Article ID 362126, 11 pages, 2015. https://doi.org/10.1155/2015/362126

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CBD Gummies for Flight Anxiety: The Complete Guide

CBD gummies for flight anxiety

Do CBD Gummies for Flight Anxiety Really Work?

CBD products have been increasing in popularity in recent years, and for good reason. CBD may help with a number of issues such as chronic pain and lack of quality sleep.

Some CBD users have raved that CBD has helped ease their anxiety. If you are reading this article, you may be asking yourself this question: do CBD-infused gummies really work to ease fear of air travel?

Yes, they may help calm your fear and stress related to air travel. Studies suggest that cannabidiol (CBD), the primary cannabinoid in marijuana, may have anxiolytic properties (1). More research is needed to determine the efficacy of CBD in treating fear of flying, but many individuals have reported success with using CBD-infused gummies for this purpose.

This article will help you understand what CBD-infused gummies are and how they work to manage flight induced anxiety.

What are CBD gummies?

CBD gummies
CBD gummies

One way to consume CBD is by eating CBD-infused gummies, which are like regular candy gummies except they contain CBD oil. Many people use gummies to manage travel related stress.

CBD-infused gummies come in different formulations:

  • Full-Spectrum CBD – contains all the compounds of hemp plants, including THC, terpenes, and flavonoids.
  • Broad Spectrum CBD – does not contain THC, but other compounds like flavonoids and terpenes are present.
  • Isolate CBD – This is the purest form of CBD, meaning that terpenes, flavonoids, THC, and other components are not present.

Although CBD can be extracted from both hemp and cannabis types of marijuana, only CBD extracted from hemp is legal at the federal level in the U.S. This is because unlike cannabis, hemp contains a very small 0.3 percent or less of THC. Federal law prohibits CBD oil and products containing more that 0.3 percent THC.

How much CBD should I take for flight anxiety?

The amount of CBD needed will vary from person to person. You should start with a low dose gummy and increase gradually over several days. For example, to begin with a smaller dose, you may take a smaller dose by cutting a 50-mg. gummy into halves or fourths.

For most people,calmness associated with taking CBD can be achieved with doses ranging between 10-30 mg. daily. Some individuals may require larger doses (up to 50 – 100mg) in order to feel a calm state prior to flying.

Benefits of Using CBD Infused Gummies for Flight Anxiety

An enjoyable flight
An enjoyable flight

Helps promote calm and alleviate anxiety

By interacting with your endocannabinoid system, CBD can help relax the stress response region of your brain. In turn, you may be more patient and at ease when dealing with anxiety-inducing activities at the airport like a rerouted flight or an emergency when flying.

Pain relief during flights

Pain of any kind can worsen anxiety. Gummies help you manage inflammation and pain that would otherwise make your travel challenging and unpleasant.

Traveling for many hours and sleeping on a plane or on uncomfortable mattresses can lead to body aches and pains. If this is true for you, gummies may help you manage the achiness.

In addition to the gummies, you can use CBD cream topically to target areas of muscle or joint pain, making your travel experience more comfortable.

Ease jet lag

Another benefit of CBD-infused gummies is that they may help ease jet lag.

Stress and anxiety over traveling may induce insomnia. As the CBD in the gummies provide calming effects, you may find it easier to go to sleep and stay asleep. This, in turn, helps ward off jet lag.

Other benefits of using CBD to ease your fear of flying include:

  • Easy accessibility. CBD products are easy to access online and at over-the-counter CBD pharmacies.
  • CBD oil may help with dry skin when traveling.
  • CBD pain cream can help soothe cramped, aching muscles that can occur when sitting for long periods.

Safety and effectiveness

Gummies (and other CBD items) are safe and may offer effective alternatives to prescription medications for anxiety and pain relief. A side effect of many anxiety and pain medications is that they can become addictive. CBD is not addictive, even after prolonged use.

Does CBD calm anxiety immediately?

Some people find relief from their symptoms in a short amount of time, but in most cases it may take several days or more of daily doses for the effects of CBD to be felt. The degree of calm one experiences can vary, depending on the individual and their own tolerance levels. By taking a daily gummy for several days well in advance of your trip, you will know how your body reacts and can determine how many gummies will be enough to manage travel anxiety.

It’s important to note that CBD is not a cure for anxiety but rather a way to manage the symptoms associated with it.

If you are looking for immediate calmness, there are other methods that may be more effective in the short term such as mindfulness and relaxation techniques, or talking through your worries with a therapist or support group. Consult with a medical professional before incorporating CBD into your anxiety management plan.

Ultimately, CBD may provide calm for some people, but remember to take time for yourself and explore all the options available for managing anxiety. With patience and dedication, you may be able to find calmness in many different ways.

What should I know before taking CBD Gummies for flight anxiety?

While the gummies can help manage travel anxiety, there are a few caveats you should know ahead of your trip.

Unclear rules about carrying CBD during a flight

Although CBD is easily accessible in the US, the legalities around CBD are still murky and vary from state to state. The laws regarding CBD are even more varied from country to country.

Can you take CBD edibles on an airplane?

While the legal status of CBD and other forms of cannabis can vary widely, the Transportation Security Administration (TSA) allows travelers to bring certain forms of hemp-derived CBD products on the plane with them in their carry-on luggage. However, it is your responsibility to confirm that your CBD products meet TSA guidelines before attempting to travel with them; failure to do so could result in confiscation or other legal consequences. Furthermore, as some states have laws prohibiting the sale and/or possession of hemp-derived CBD, travelers should be aware that local laws may affect their ability to bring such items through airport security.

Will TSA take my CBD gummies?

TSA rules must be considered if you plan to carry gummies on a plane. According to TSA’s “What Can I Bring” website, products containing hemp-derived CBD that contain less than 0.3 percent THC are generally permissible in carry on and checked baggage.

Therefore, be sure your gummies contain no more than 0.3 percent THC and that all ingredients meet federal and TSA travel requirements. If you are bringing CBD tinctures and creams with you, they should be less than 3 ounces in volume.

With that said, possession of marijuana and certain cannabis products remains illegal under federal law even though some states allow for recreational use. TSA officers may confiscate your items even if they merely suspect a violation of federal law. The TSA will refer all suspected violations of law to the police.

If traveling abroad, you should research CBD laws in each country before you fly.

For example, many countries in Europe like Iceland, Montenegro, and Monaco do not consider CBD legal. In addition, CBD is illegal in most Asian countries, like Cambodia and Vietnam. And while a few countries in South Africa consider CBD legal, most other African countries do not.

Why you shouldn’t take them for the first time on your flight

Taking CBD for the first time on your flight is not advisable. This is because different people react to CBD differently. On long flights especially, it can be difficult to gauge how one might react if they take it for the first time in an enclosed space with few resources to manage any potential side effects or complications.

May induce anxiety

While CBD is known to provide calming effects, THC may induce anxiety or panic attacks in certain people. This means that some people may negatively react to full-spectrum CBD gummies, as they contain both THC and CBD. A broad spectrum CBD might be a better choice.

May cause drowsiness

CBD may cause drowsiness and fatigue, which could compromise safety when traveling at high altitudes with limited access to assistance.

May react adversely with other medications

CBD may interact with other medications that you may be taking. Check with your doctor before using CBD if you are taking any other medications, as it could interfere with these medications and cause adverse effects.

When Should I Use CBD Gummies for Flight Anxiety?

Days before a flight

Take daily doses at least a few days before you travel. This will help you determine how your body reacts to taking CBD oil or CBD-infused gummies as well as the most effective dose to address anxiety and pain.

During your flight

Once you know the correct dose and how your body responds, taking a gummy before your flight can help you manage your fear of flying and support a relaxing experience. You can take one right before you go through airport security to give it ample time to work.

After a flight

Jet lag is not uncommon when traveling, especially if you are on a plane for many hours. For this reason, taking a gummy after your flight can help promote promote calm, rest, and restorative sleep. This can help ease jet lag.

Tips To Remember When Carrying CBD Gummies for Flight Anxiety

Be honest with airport security personnel.
Be honest with airport security personnel.
  • Research the cannabis state laws of the particular state you are traveling to. Additionally, find out the legalities surrounding CBD products in different countries beforehand.
  • Speak to your doctor before taking gummies, especially if you are on any medications.
  • Ensure your gummies contain less than 0.3 percent THC. This is the legal limit in the U.S.
  • THC may appear on drug tests. Avoid full spectrum gummies if passing a drug test is a concern for you. Instead, use gummies containing broad spectrum CBD.
  • Do not use gummies for the first time during your flight. Although they are safe and are not known to present major negative side effects, it is always best to use them several times before your flight so you know the effects beforehand.
  • Do not attempt to hide your gummies or any CBD product from TSA officers. Instead, be upfront about them. If you have a medical marijuana license, bring it with you.
  • If you want to bring gummies containing delta 8, you should check with the airline you are using before traveling with them.Some airlines do not allow passengers to transport any form of gummies containing delta 8 or delta 9 on their aircraft. If a passenger is found to have them in their luggage or on their person during travel, airline personnel will confiscate them and may issue legal consequences.
  • Flight delays and cancellations are common and almost unavoidable. Leave adequate time in your itinerary for the unexpected to help minimize anxiety.
Air travel can be an enjoyable experience.

Editor’s note:

We sell CBD products, but our goal is to provide you with the best information possible to help you learn about CBD and make informed decisions when choosing products.

At Innovative Extracts, we understand that providing the highest quality products requires a unique set of skills and knowledge. Our founders have worked hard to build a team of experts who bring innovative solutions and processes to the table. We strive for excellence in all aspects of production from seed selection to finished product packaging. This allows us to ensure that each customer receives not only the best possible experience with our products but also peace of mind in knowing that their purchase is backed by professionals passionate about delivering safe, effective, and reliable products.

Works cited

1. Shannon, Scott et al. “Cannabidiol in Anxiety and Sleep: A Large Case Series.” The Permanente journal vol. 23 (2019): 18-041. https://doi.org/10.7812/TPP/18-041

2.de Mello Schier, et al. “Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa.” CNS & neurological disorders drug targets vol. 13,6 (2014): 953-60. doi: 10.2174/1871527313666140612114838

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Which CBD Strain is Best for Anxiety?

Which CBD Strain is Best for Anxiety?

Which CBD Strain is Best for Anxiety? 12 Must-Try High CBD Strains

Let us be honest; the world has been quite an anxious place in recent years, resulting in many people using a little something to calm their nerves. In fact, the Anxiety and Depression Association of America (ADAA) reports that about 19.1% of the U.S. adult population suffers from anxiety disorders.

With people seeking an alternative solution to prescription medications to relieve stress and reduce anxiety, many have landed on CBD, thanks to its stress-relieving effects. Some users have also praised high-quality CBD products for improved and restful sleep.

However, as the CBD market continues to grow, it may be a tad difficult to figure out what CBD strain is best for anxiety disorders. Fortunately for you, we have curated this guide to help you get started.

How Do CBD Strains for Anxiety Work?

Before we get to this, we need to address the elephant in the room.

Yes, high CBD strains for anxiety help you relax and provide you with anxiety relief.

You may consume these strains by smoking CBD flower or using products infused with CBD. These include gummies, oils, creams, and tablets. However, more on that later.

Understanding the Endocannabinoid System


We need to explore the endocannabinoid system (ECS) found in your body to better understand how CBD interacts with it to relieve pain, stress, and anxiety.

ECS ensures different functions and processes are regulated and running smoothly. These include appetite, memory, mood, and sleep. In addition, everyone has an ECS system, whether you use cannabis or not.

ECS comprises three major components: enzymes, receptors, and endocannabinoids. Endocannabinoids are similar to the cannabinoids found in CBD. Your body produces endocannabinoids when needed to ensure internal processes run smoothly.

So far, only two types of endocannabinoids have been identified by experts:

  • Anandamide (AEA)
  • 2-arachidonoylglycerol (2-AG)

Endocannabinoids bind to the endocannabinoid receptors all over your body to alert the ECS that certain processes need to take action.

  • CB1 receptors – present in the central nervous system
  • CB2 receptors – often found in the peripheral nervous system

Endocannabinoids can bind to either receptor to provide varying effects. For example, endocannabinoids may bind to CB2 receptors in the immune cells as a sign to the ECS that your body is experiencing inflammation.

Finally, two enzymes help break down the endocannabinoids once their function has been completed. These are:

  • Fatty acid amide hydrolase – breaks down AEA
  • Monoacylglycerol acid lipase – breaks down 2-AG

By regulating homeostasis, ECS helps the body recover when an outside force, say inflammation or fever, sets you off balance.

How Do CBD Strains Manage Your Anxiety Levels?

Research on how CBD reduces general and social anxiety and stress levels is ongoing. However, some experts believe CBD boosts homeostasis by preventing endocannabinoids from being broken down by enzymes.

Additional research suggests that CBD binds to an endocannabinoid receptor in your body to provide its vast benefits. It is evident that CBD strains help manage anxiety, relieve pain, and improve your sleep.

In turn, you can stay calm, relaxed, and happy. Additionally, CBD does not get you high.

What About THC Strains for Anxiety?


Unlike CBD, THC interacts with the ECS by binding to the CB1 and CB2 receptors. For this reason, THC provides a range of effects on your body and mind. Some of these include reducing pain and stimulating your appetite.

Unfortunately, high THC may have negative effects like increased anxiety and paranoia. Another disadvantage of THC is its psychoactive effects (aka, it will get you high).

So, stay clear of high THC strains when dealing with anxiety. Instead, you want to go for high CBD strains or balanced strains. This is because, in low doses, THC helps reduce anxiety.

Do Terpenes Help With Anxiety?


Terpenes are in charge of the different aromas in CBD strains. In addition, the terpene profile also determines a certain strain’s effects, whether sedating or energizing.

Some of the most common terpenes in CBD strains for anxiety include limonene, caryophyllene, and myrcene.

12 Best CBD Strains for Anxiety

 

Best CBD Strains for Anxiety

Cannabis strains are categorized into the following major strains: indica, sativa, and hybrid.

While the major difference between indica and sativa strains is structural, each strain will have varying effects. Indica strains are used to treat anxiety and pain management and improve your sleep since they are high in CBD.

Conversely, sativa-dominant strains are best if you want a burst of energy. Unfortunately, these strains are unsuitable for reducing anxiety since they have a high THC ratio.

Hybrid strains refer to a crossbreed of indica and sativa strains. For this reason, they may be indica-dominant or sativa-dominant strains.

If you are asking yourself what CBD strain is best for anxiety, below are the 12 best options.

  1. Harlequin

Although a sativa-dominant hybrid strain, harlequins have a CBD: THC ratio of 5:2. For this reason, it is perfect for reducing anxiety. In addition, users love that harlequin provides clear-headed alertness, allowing you to feel relaxed and not sedated.

Low THC content is also great for dealing with an anxiety disorder, as it helps you feel more relaxed and calm.

  1. Cannatonic

Cannatonic is another great high CBD strain for reducing anxiety. With a CBD content as high as 17% and less than 6% THC, this strain offers you relaxing yet uplifting qualities without any psychoactive effects of THC.

Additionally, its profile makes it among the go-to medical marijuana strains. However, you will be surprised to know that cannatonic is not as sedative as its name implies.

  1. Sour Tsunami

Sour Tsunami is also a favorite in the medical marijuana community for a good reason. This high CBD sativa-dominant strain with about 11% CBD and less than 7% THC was specifically bred by crossing NYC Diesel and Sour Diesel.

Why? For its high CBD content.

Sour Tsunami users have reported a significant decrease in anxiety and depression. Additionally, low THC levels work to provide relief from inflammation and pain.

This medicinal strain will leave you feeling relaxed and clear-headed, making it a great CBD flower for anxiety.

  1. Harle-Tsu

Created by the late Lawrence Ringo, Harle-Tsu is a hybrid cross between some of the highest CBD strains, Harlequin and Sour Tsunami. With about 11% CBD and less than 1% THC content, this hybrid strain provides strong anti-anxiety and calming effects.

However, you will not feel zoned or stoned as the strain has virtually no THC. In addition to stress and anxiety relief, users report feeling relaxed and happier.

Harle-Tsu also provides inflammation and pain relief.

  1. Canna-Tsu

As the name suggests, Canna-Tsu is a hybrid strain of Cannatonic and Sour Tsunami. It is created equal, meaning it has a 1:1 CBD/THC ratio.

This high CBD strain helps reduce high anxiety levels by offering you calming effects. Although this strain will not get you stoned, it is also not recommended for beginners with a general or social anxiety disorder.

In addition to reducing anxiety, Canna-Tsu also packs anti-inflammatory properties. This strain is suitable for day or nighttime use.

  1. Sour Space Candy

Sour Space Candy is part of the high CBD, low THC hemp strains on the CBD market. This strain is advisable for daytime use as it reduces anxiety and depression while still allowing you to focus.

If your social anxiety disorder is keeping you from social interactions, Sour Space Candy helps uplift your mood without the THC high.

  1. ACDC

Although a sativa-dominant strain, ACDC is one of the highest CBD strains that helps manage stress and anxiety. With a CBD: THC ratio of 20:1, this strain will make you feel calm, relaxed, and happy.

Additionally, ACDC does not cause any psychoactive effects. The only downside of using ACDC cannabis strain is that it causes dry mouth. However, its benefits as a medicinal strain far outweigh the disadvantages.

  1. Elektra

If you are looking for a low THC high CBD strain that reduces your anxiety, calms and relaxes you but has no high effects, then Elektra is it. This strain is particularly great for beginners and helps manage depression and anxiety.

Elektra is also great for daytime use, thanks to its CBD: THC ratio. However, keep in mind that its aroma and pungent smoke get mixed reviews from users.

  1. Ringo’s Gift

This high CBD hybrid strain is a cross between ACDC and Harle-Tsu. Users love the reduced anxiety and stress levels they experience from using this strain.

Ringo’s Gift also helps improve your sleep quality, especially if your anxiety disorder keeps you awake at night.

  1. Remedy

This 14% CBD strain gives you a calm and peaceful mellow effect without any mind or body psychoactive effects. As the name suggests, Remedy is great for stress and anxiety control, helping you enjoy calm and Zen moments.

Besides its anti-anxiety properties, Remedy is used to treat inflammation, pain, and even seizures.

  1. Trident

This CBD strain for anxiety boasts about 12% CBD and is less than 6% THC. It is a go-to strain for people looking to stay mentally focused with controlled stress and anxiety levels.

While most users report feeling relaxed from using this strain, you may experience mild psychoactive effects. For this reason, Trident is not recommended for beginners.

  1. Lifter

Lifter has 18% CBD and less than 1% THC. For this reason, it is good for managing anxiety disorders as it has uplifting effects while keeping you relaxed.

Although it has a weird “funky cheese with hints of fuel” aroma, users rave that this high CBD strain makes them happy and relieves their pain.

Things To Keep in Mind When Trying CBD for Anxiety


Things To Keep in Mind When Trying CBD for Anxiety

Although high CBD strains help manage anxiety, you will find that some of them contain some amount of THC. This is because THC (at low doses), paired with CBD and terpenes, helps ease anxiety.

Determining how any amount of THC will affect you (or anyone else) is quite challenging. Below are tips to remember when trying out the best CBD strains for anxiety.

  • Start with a low THC high CBD strain, then give it time to work before switching to a new strain.
  • Consider exploring non-smoking methods to protect your lungs. This could be by using gummies (super tasty and fun!) and oils for anxiety.
  • Avoid activities like driving for about 6 hours or more after use, especially if you are experiencing any effects.
  • Consult your health practitioner before using CBD products if you are on anti-anxiety medication.
  • Check your state’s legislation regarding legal THC and CBD levels. Remember to counter-check the same when traveling from one state to another since the legislation varies in each state.

Frequently Asked Questions

  1. What Makes a Strain High in CBD?

Ideally, high CBD strains have more than 10% cannabidiol(CBD) and less than 0.3% THC. The THC must be within the legal limit in the US. Additionally, the low THC allows you to reap its benefits while avoiding the high, which causes adverse effects for people with anxiety disorders.

  1. How Do You Use CBD Hemp Flowers for Anxiety?

Smoking is one way to use high CBD hemp strains for their anti-anxiety and therapeutic benefits. Additionally, vaping and dabbing can also help you reap the benefits.

However, other methods of consuming high CBD products, like gummies and oils, are also extremely effective for managing anxiety.

Innovative Extract’s CBD Products for Anxiety

CBD Products for Anxiety

Finding CBD-infused products for managing anxiety is not an easy task. This is because there are many factors to consider, like the CBD type, concentration, hemp source, and third-party laboratory tests, before buying.

Here at Innovative Extracts, we understand that quality CBD products are important for your health and overall wellness. For this reason, we ensure that our hemp is grown on safe farms in the United States and extracted using the best practices in the industry.

Our broad-spectrum CBD and full-spectrum CBD products for anxiety are tested by an independent third-party lab to ensure they are quality and safe for your health.

If you are ready to get your life back from anxiety and enjoy precious moments with loved ones, try out our anti-anxiety range today. You can also contact us to learn more about our products.

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CBD Strains for Sleep – Which One is the Best?

CBD Strains for Sleep - Which One is the Best

CBD Strains for Sleep – Which One is the Best?

A good night’s sleep is essential for your health and general well-being. Unfortunately, anxiety, stress, pain, and never-ending video streaming services can affect your sleep and keep you up all night.

While many people having trouble sleeping peacefully or with sleep disorders, like insomnia, reach for sleep medications, the effects are simply hard to ignore. These include over-dependence, resistance, and even addiction!

As a result, many people have turned to CBD strains for sleep and relaxation. However, not all CBD strains improve sleep.

So, this article is for you if you are looking for the best CBD products and strains for sleep. Let’s get started.

What Are CBD Strains?

CBD strains refer to different CBD varieties and how they affect your sleep quality.

But what is CBD?

CBD, cannabidiol, is among the active compounds found in hemp and marijuana plants.

CBD is often extracted and used to make CBD products like CBD gummies, tinctures, creams, and tablets. However, you can also smoke cannabis plants to benefit from CBD.

Before we delve deeper, one thing to note is that hemp and marijuana plants are scientifically different names for the same plant. They are called cannabis plants, flowering plants from the Cannabaceae family.

However, they are legally different.

How?

Hemp means cannabis plants with a THC content of less than 0.3%. On the other hand, Marijuana refers to a cannabis plant with a THC content of more than 0.3%.

In addition, marijuana is often interchangeably used with “weed” to refer to cannabis that will get you high.

Could Any CBD Strain Help With Sleep?

Cannabis strains can be largely classified into two groups, Indica and Sativa.

Indica refers to a short and bushy cannabis plant, while Sativa refers to a long and slender cannabis plant. However, other than the structural reference, each strain has different effects.

i). Indica strains

These are best for sleep aid as they have sedative effects. This is because they have a higher CBD content. However, note that this does not necessarily mean a lower THC content.

For this reason, cannabis indica will make you more calm, relaxed, and sleepy. Additionally, indica strains are used for pain management.

ii). Sativa strains

These are more energizing and give feelings of euphoria. They are best preferred when you want an energy boost. This is because they have more THC than CBD.

iii). Hybrid strains

These refer to a mix of Indica and sativa strains. However, note that these strains will have different effects depending on how the strain was made. For this reason, you may find Indica-dominant hybrids or Sativa-dominant hybrids.

However, while the Indica strain is considered the best CBD strain for sleep, the terpene profile, THC, and CBD content in a certain strain will affect efficiency in managing sleep disorders.

How Does CBD Work to Improve Your Sleep Quality?

Research has found that sleep is affected by many things, from chronic pain to stress and anxiety.

So, how does cannabis use help your sleep problems?

Your body contains an ECS (endocannabinoid system) that regulates and controls various processes. These include temperature control, learning and memory, pain control, appetite, inflammatory response, and your immune system.

In addition, the ECS system releases endocannabinoids, similar to the cannabinoid compounds found in cannabis strains.

When you take CBD for sleep regulation, the cannabinoids interact with the ECS receptors in your brain to support and boost your body’s physiological processes. This is why you will feel sedated and fall asleep faster after taking CBD products, like CBD gummies, for sleep.

CBD Vs. THC for Sleep, Which is Best?

CBD vs THC for sleep

As we mentioned in the article, CBD can be extracted from either hemp or marijuana plants. For this reason, there may be traces of THC in the CBD products, depending on where it was extracted and the type of CBD formulation.

So, How Do Different Cannabis Strains Affect Your Sleep Quality?

One study conducted in 2008 found taking cannabis strains with more THC content than CBD to be more beneficial in managing sleep disorders. This is because THC is a sedative and will decrease REM sleep(rapid eye movement) which causes dreams while you sleep.

By reducing REM sleep and dreaming less, you spend more time in deep sleep, which is more restful and restorative. This is especially true if you have PTSD since less dreaming means fewer nightmares and more restful sleep.

However, it’s important to note that REM sleep also benefits your immune system. Unfortunately, overreliance on high THC content could impair the quality of your sleep and affect your sleep cycle.

Therefore, it is safer and more beneficial to use high CBD strains for sleep management. This could be CBD products made from broad-spectrum CBD extract or infused with other essential cannabinoids, not THC, to promote deep and restorative sleep.

Hemp strains are preferred in this case since they are low THC strains.

Are There Side Effects of Using Cannabis for Sleep Aid?

Side effects of high THC strains for sleep aid include:

  • Anxiety
  • Psychoactive effects
  • Impaired memory on the next day
  • Sleepiness on the next day

Cannabis research has also shown that long-term use of THC as a sleeping aid could adversely affect your sleep and overall health. These include:

  • Taking longer to fall asleep
  • Frequent awakenings
  • Less time on deep sleep
  • Overall less sleep
  • Cannabis withdrawal effects like strange dreams
  • Reduced grey matter volume in the brain
  • Chronic bronchitis when smoked

Does A Low Dose of THC Help With Sleep?

While there’s not enough cannabis research to support THC use in managing sleep problems, a lower dose is always advisable. In addition, the legal THC content allowed in CBD products is 0.3 % or less.

This means that most of the CBD gummies and tinctures for sleep you will find in the market will either be broad-spectrum CBD(aka THC-free) or full-spectrum CBD( less than 0.3% THC content).

What Are the Best CBD Strains for Sleep

Finding the best CBD strains is not a walk in the park, especially for beginners. Ideally, you want to go for Indica strains or Indica dominant hybrids with a more CBD and low THC content or a well-balanced CBD to THC ratio.

Below are the best CBD-dominant strains for insomnia and other sleep disorders.

  1. Harlequin

Harlequin is among the most popular strains with a 5:2 CBD:THC ratio. It provides you with a clear-headed and alert state of mind without making you drowsy. However, you will experience mild euphoria.

Harlequin helps manage pain and anxiety. In addition, most users find that it enhances whatever activities they are engaged in.

  1. Ringo’s Gift

With a 13:1 CBD:THC ratio, Ringo’s Gift soothes and helps you relax without presenting a sedative effect. For this reason, it is used to alleviate pain and manage anxiety, PTSD, and migraines.

Ringo’s Gift, a hybrid cross of ACDC and Harle-Tsu strains, can also be found in strains as high as 24:1. Additionally, its notes range from spice and mint to citrus and pine.

  1. Harle-Tsu

Harle-Tsu is a cross between Harlequin and Sour Tsunami, both on this list. The CBD dominant strain boasts a CBD:THC ratio of 20:1. However, remember that this ratio varies depending on the season and the grower.

Most users love this CBD strain because it manages inflammation and relieves chronic pain. Additionally, its earthy notes with hints of pine and pepper combined with its subtle sweetness make it even more pleasant.

  1. Cannatonic

Unlike the name suggests, this 2:1 CBD:THC strain will not leave you feeling sedated. Quite the contrary, Cannatonic helps you relax and unwind while providing a mellow high.

Cannatonic is often considered a medical strain and helps users treat migraines. Other benefits you can get from this strain include managing anxiety and chronic pain(all resulting in a good night’s sleep).

In fact, some users claim that the pain melts away in about 10 minutes of using this CBD strain.

  1. Sour Tsunami

Last on our list is Sour Tsunami. This strain has a CBD:THC ratio of about 3:1, making it perfect for managing inflammation and alleviating pain without the high caused by THC.

Sour Tsunami is popular among users looking to reap the medicinal benefits of high CBD without getting high! Additionally, its scent is similar to diesel but with sweet undertones, thanks to its cross between NYC Diesel and Sour Diesel strains.

What is the Best Way to Use CBD Strains for Sleep?

CBD gummies for sleep

CBD strains come in various forms. These include gummies, tinctures, oils, creams, tablets, and pre-rolls. For this reason, each form will take a different time before you can experience the CBD benefits.

Below are a few ways to use CBD hemp flowers for sleep aid.

i). Sublingual – This method involves placing CBD oils and tinctures under the tongue, where they are absorbed into your bloodstream.

It is preferable if you want to experience CBD flower benefits fast or simply don’t like smoking.

ii). Edible – This delivery method allows you to chew CBD-infused candies or gummies. It is perfect for beginners trying out CBD products.

Have we mentioned that CBD gummies are super tasty?

Unfortunately, edibles take longer to provide you with CBD benefits. This is because the CBD gummies need to be first processed(hello digestive system) and then absorbed into the bloodstream.

iii). Topical – Topical CBD treatments are used to target specific areas causing you pain or discomfort. Once applied to the skin, the CBD is immediately absorbed by surrounding tissue to provide you relief.

This method is also the least effective compared to using tinctures, smoking, or eating an edible.

iv). Inhalation – This method delivers CBD directly to the bloodstream. This can be by smoking the CBD hemp flower, dabbing, or vaping.

Different CBD delivery methods will have varying bioavailability(how much THC will reach your bloodstream). For example, inhalation provides the highest bioavailability since THC is directly absorbed.

Conversely, edibles have the least bioavailability since some THC is lost during the digestive process.

When Should You Take CBD for Sleep?

Different CBD formulations will take different times to affect you. For this reason, it is important to time when you take CBD strains for insomnia with your bedtime.

Edibles are a good starting point in this case. Although they take longer to kick in, they also last longer in your system.

This means you can take a CBD gummy about 40 minutes to an hour before bedtime and stay asleep longer while the CBD is still in your bloodstream.

However, keep in mind that everyone’s metabolism is different. While it may take some people shorter to feel the sedative effects of cannabis strains, it may take others longer.

Conclusion

Suffering from a sleep disorder can have adverse effects on your health and wellness. These effects include fatigue, stress, low productivity levels, and unhappiness.

Many cannabis users have reported relief from pain and improved sleep. However, there is still a lot of debate between CBD and THC and which is best for insomnia patients.

Unfortunately, although a sedative, you may find that THC causes you to be more anxious or paranoid. In this case, CBD strains with a low THC content will be best for you. In addition, CBD has fewer side effects, making it a great option for pain relief, anxiety, and sleep.

How Does Innovative Extracts Help Improve Your Sleep Quality?

Restorative and restful sleep is important to us, just as it is to you. Fortunately for you, our THC-free CBD gummies allow you to get the full benefits of CBD without experiencing the high feeling.

Our gummies are also packed with melatonin which helps you relax and sleep better. Finally, if you want to sleep faster, our broad spectrum CBD + CBN tincture enhances CBD effects and provides additional benefits.

So, check out our CBD for sleep range if you are ready to switch off and wake up feeling relaxed and well-rested. You can also contact us for questions and inquiries about our CBD products.

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LANGUAGE OF CBD

Helpful Terms Below!

Curious about trying CBD, but don’t know what all the fancy words you’ve seen online mean? Read on below for some important terms!

2-AG – aka 2-arachidonoylglycerol, the most common endocannabinoid found in the brain.

AEA – aka anandamide, the second most common endocannabinoid found in the brain.

Broad spectrum – does not contain any THC, but contains all of the other cannabinoids found in the hemp plant.

Cannabis sativa – scientific name of the plant species that we use to grow our hemp, which is then used to make our products. This is the same plant that is used to grow marijuana as well. The important differences between hemp and marijuana are described below.

CB1R – cannabinoid receptor type 1, which is found mostly in the brain, but also in the liver, heart, and intestines.

CB2R – cannabinoid receptor type 2, which is found mostly in immune system cells, including in the intestines.

CBD – aka cannabidiol, is the second-most common phytocannabinoid. It weakly binds to and blocks CB1R and CB2R, but it is not clear if its effects on the body are through these interactions. It can also interact with other parts of the endocannabinoid system. It is the primary ingredient in our products and is thought to help treat many different diseases. It is non-addictive, does not have psychoactive effects, and does not cause people to feel “high.”

Endocannabinoid – refers to the molecules that our bodies make that can bind to receptors in the endocannabinoid system, leading to effects on the body.

Endocannabinoid system – refers to the cell signaling system in our bodies that has been shown to play a role in many different diseases, including chronic pain, multiple sclerosis, anxiety, depression, seizures, obesity and certain kinds of cancer. Fore more information, check out our endocannabinoid system post.

Full spectrum – contains all of the cannabinoids found in the hemp plant, including CBD and THC, though concentration is less than 0.3% per the law.

Hemp – cannabis that contains less than 0.3% of THC, the psychoactive phytocannabinoid. All of our products come from hemp.

Marijuana – aka weed, cannabis that contains more than 0.3% THC, the psychoactive cannabinoid. This is the kind of cannabis that has been used recreationally for decades. Our products are not made from marijuana.

Phytocannabinoid – refers to molecules that are made in plants and that can interact with the endocannabinoid system. The two most common phytocannabinoids are THC and CBD.

THC – aka tetrahydrocannabinol, is the most common phytocannabinoid and the most well-studied. It binds to and activates both CB1R and CB2R, and has many effects on the body, including stimulating appetite, causing increased body temperature, and psychoactive effects that make people feel “high.”

Tincture – plant or animal extract that is dissolved in a solution. In the case of our products, the tincture consists of hemp extract, the components of which determine whether the product is considered full spectrum or broad spectrum.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Consult your physician prior to use if you are pregnant, nursing or using other medications.